Toxicology risk assessment (TRA)

Regulations in the UK, EU, US, and other regions require manufacturers to demonstrate that their products are safe before they are placed on the market. A toxicological risk assessment provides the documented evidence of safety needed for compliance.

Yes. Under cosmetic regulations, all products must undergo a safety assessment. Even products that do not strictly fall under the cosmetic definition may still benefit from or require a toxicological risk review to demonstrate due diligence and protect consumers.

You’ll need to supply full details of your formulation (INCI and raw material composition), raw material safety data, manufacturing information, and supporting documents such as stability or microbiology results, if available.

The timeline depends on the completeness of the information provided and the complexity of the product, but we aim to work closely within your timeframe and constraints. Our customer service offer is designed to make your life as easy as possible with a dedicated point of contact in most cases and a detailed schedule to keep you up-to-date with the process.

Our assessors will provide clear feedback on the safety concerns identified and suggest practical solutions, such as reformulation, concentration adjustments, or additional supporting data.

In addition to a toxicological risk assessment, cosmetic and personal care products must undergo a range of compliance steps before being placed on the market. These typically include a full Cosmetic Product Safety Report (CPSR), creation of a Product Information File (PIF), labelling and INCI compliance checks, stability and microbiological testing, and notification on the relevant regulatory portals. Depending on the product and its claims, further services such as claims substantiation, Good Manufacturing Practice (GMP) verification, and ongoing post-market surveillance may also be required. ADSL can support with all of these and work with you to create a clear plan to bring your product to market as efficiently as possible.

Formed in 2008, our fully qualified, independent team of Chartered Chemists, Toxicologists, Microbiologists and Regulatory experts specialise in formulation and testing services within the cosmetic, household goods, food and industrial sectors. We are a UKAS accredited testing laboratory offering a range of accredited and non accredited microbiological tests. Our team includes individuals with a host of industry qualifications including Fellows of the Royal Society Of Chemistry and a “Chartered” Chemist and Scientist, Members of The Society Of Cosmetic Scientists, Members of the British Toxicology Society, Members of Society of Dermatology, Members of International Society of Dermoscopy, Members of European Academy of Dermatology & Venereology (EADV) along with Chem CSci, CChem FRSC and PhD attainment. With our exceptional expertise and complementary skills in manufacturing, process controls, industry regulation, health and safety, marketing, and project management we are with you every step of the way to see your product through to successful market launch. Furthermore, our technical consulting helps many businesses by cost effectively filling gaps in their skills and knowledge base and providing a fresh perspective and strategy on the best way forward. Fundamentally we have the the knowledge and know-how to successfully take your cosmetic product to market. Your product inside out.